BioScience Trends. 2017;11(6):307-315. (DOI: 10.5582/ddt.2017.01061)

Potential of Piper betle extracts on inhibition of oral pathogens.

Phumat P, Khongkhunthian S, Wanachantararak P, Okonogi S


SUMMARY

In the present study, antimicrobial activity of Piper betle crude ethanol extract against 4 strains of oral pathogens; Candida albicans DMST 8684, C. albicans DMST 5815, Streptococcus gordonii DMST 38731 and Streptococcus mutans DMST 18777 was compared with other medicinal plants. P. betle showed the strongest antimicrobial activity against all tested strains. Fractionated extracts of P. betle using hexane, ethyl acetate, and ethanol, respectively, were subjected to antimicrobial assay. The result revealed that the fractionated extract from ethyl acetate (F-EtOAc) possessed the strongest antimicrobial activity against all tested strains. Its inhibition zones against those pathogens were 23.00


KEYWORDS: Piper betle, oral pathogen, extract, antibacterial activity, antifungal activity

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