BioScience Trends. 2017;11(6):316-322. (DOI: 10.5582/ddt.2017.01055)

Effects of Caesalpinia sappan on pathogenic bacteria causing dental caries and gingivitis.

Puttipan R, Wanachantararak P, Khongkhunthian S, Okonogi S

The present study explores antimicrobial activities of Caesalpinia sappan extracts against three strains of oral pathogenic bacteria; Streptococcus mutans DMST9567 (Smu9), Streptococcus mutans DMST41283 (Smu4), and Streptococcus intermedius DMST42700 (Si). Ethanol crude extract of C. sappan (Cs-EtOH) was firstly compared to that of other medicinal plants using disc diffusion method. Cs-EtOH showed significantly higher effective inhibition against all tested strains than other extracts and 0.12% chlorhexidine with the inhibition zone of 17.5

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