BioScience Trends. 2008;2(5):277-281. (DOI: )
Effect of drug-polymer binary mixtures on the in-vitro release of ibuprofen from transdermal drug-in-adhesive layers.
Ho KY, Ord M, Dodou K
SUMMARY
We report on the formation of eutectic mixtures of ibuprofen using two different polymers together with investigations on the in-vitro release of ibuprofen from drug-in-adhesive layers. Ibuprofen, literature melting point (m.p.) = 73.5-76.5
KEYWORDS: Transdermal patches, Drug-in-adhesive, Ibuprofen, Eutectic mixture, Thermodynamic activity
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