BioScience Trends. 2009;3(3):97-103. (DOI: )
A validated stability-indicating HPLC method for analysis of glabridin prodrugs in hydrolysis studies.
Jirawattanapong W, Saifah E, Patarapanich C
SUMMARY
A simple, selective and precise stabilityindicating HPLC method for determination of glabridin diacetate and dihexanoate prodrugs was developed, validated and applied to the enzymatic and chemical hydrolysis studies. The chromatographic separation was achieved on a reverse phase C18 (Thermo Hypersil-Keystone, 250
KEYWORDS: Glabridin, prodrugs, HPLC, validation, hydrolysis studies