Stability studies of the effect of crosslinking on hydrochlorothiazide release.

BioScience Trends. 2009;3(3):136-142. (DOI: )

Stability studies of the effect of crosslinking on hydrochlorothiazide release.

Elmeshad AN, Darwish MK

SUMMARY

The aim of this study was to determine the changes in the in vitro drug release from cross-linked hard gelatin capsules containing a water-insoluble drug. An immediate release hydrochlorothiazide (HCTZ) capsule formulations containing drug, lactose, starch 1500 were prepared and exposed to accelerated stability study (40

KEYWORDS: Hard gelatin capsule, cross-linking, hydrochlorothiazide, relative humidity, starch

Full Text: