BioScience Trends. 2010;4(3):179-183. (DOI: )

Rehmanniae Radix provides most of the free fructose and glucose in Si-Wu-Tang decoction.

Ma J, Liang QD, Ma ZC, Wang YG, Liu M, Lu BB, Tan HL, Xiao CG, Zhang BL, Gao Y

Our previous study showed that free fructose is an important active constituent responsible for Si-Wu-Tang's (SWT) effect promoting hematopoiesis and immunity. However, the contribution from SWT's four ingredient drugs to the free fructose content in the SWT decoction was not clear. To answer this question, in this study, the fructose, glucose and sucrose content in the SWT decoction, in the decoctions of each single ingredient drug, and in the decoctions of the four formulae lacking each single ingredient drug were determined by HPLC-ELSD. The results showed that the fructose and glucose content in the decoction of single Rehmanniae Radix were almost the same as those in the SWT decoction. In the single Rehmanniae Radix decoction concentrations were: 4.25

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