BioScience Trends. 2010;4(6):405-411. (DOI: )

Taxonomic identification of a novel strain of Streptomyces cavourensis subsp. washingtonensis, ACMA006, exhibiting antitumor and antibacteria activity.

Yuan XW, Yang RL, Cao X, Gao JJ


SUMMARY

Taxonomically diverse and genetically specialized, marine microorganisms have great potential in generating bioactive substances. A previous study isolated a novel actinomycete strain designated ACMA006 and revealed that the fermentation broth of ACMA006 (FBA6) significantly inhibited the growth of a series of tumor cell lines. The present study examined various characteristics of the ACMA006 strain, including its morphological, physiological, and biochemical nature, and the 16S rDNA gene sequence of ACMA006 and biological activity of FBA6. The ACMA006 strain grew at an optimal temperature of 28


KEYWORDS: Streptomycetes, antitumor activity, antibacterial activity, 16S rDNA gene, phylogenetic analysis

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