BioScience Trends. 2010;4(6):484-492. (DOI: )
Comparative study on the different techniques for the preparation of sustained-release hydrophobic matrices of a highly water-soluble drug.
Abd El-Halim SM, Amin MM, El-Gazayerly ON, Abd El-Gawad NA
SUMMARY
The objective of the present study was to control the release of freely water-soluble salbutamol sulphate (SS) over a prolonged period of time by embedding the drug into slowly eroding waxy matrix materials such as Precirol
KEYWORDS: Salbutamol sulphate, controlled release, waxy materials, direct compression, hot fusion