BioScience Trends. 2007;1(2):130-135. (DOI: )

The effects of antidepressant drug on ethanol-induced cell death.

Johnson S, Williams AN, Johnson C, Ou XM

Alcoholism is a serious health problem. Alcohol-dependent subjects have many health-related problems, such as severe cognitive impairments, alcoholic liver disease and coronary heart disease, resulting from ethanol-induced cell injury or cell death. Understanding the mechanisms underlying the cell death may provide clues for novel treatment strategies to prevent alcohol-induced cell damage. Prolonged ethanol consumption causes apoptotic activity in a host of cell types

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