BioScience Trends. 2013;7(3):116-123. (DOI: 10.5582/ddt.2013.v7.3.116)

Evaluation of in vitro mutagenicity and genotoxicity of magnetite nanoparticles.

Gomaa IO, Kader MHA, Salah TA, Heikal OA

For successful application of nanomaterials in bioscience, it is essential to understand the biological fate and potential toxicity of nanoparticles. The aim of this study is to evaluate the genetic safety of magnetite nanoparticles (MNPs) (Fe₃O₄) in order to provide their diverse applications in life sciences, such as drug development, protein detection, and gene delivery. Concentrations of 10 ppm, 30 ppm, and 70 ppm (10-70 ?g/mL) of the MNPs of 8.0

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