BioScience Trends. 2015;9(2):107-115. (DOI: 10.5582/ddt.2015.01023)
A novel polysaccharide isolated from Litchi chinensis by using a simulated gastric medium and its immunomodulatory activity.
Wang LS, Hu XJ, Bi SX, Tu WS, Jing YS, Song LY, Lv WJ, Yu RM
SUMMARY
A novel polysaccharide (LCPA50-S1) with immunomodulatory activity was extracted with simulated gastric medium from Litchi chinensis, and purified by DEAE-52 cellulose column, Sephadex G-50 column and Sephacryl S-300 HR chromatography. The structural characteristics of LCPA50-S1 were expounded through complete acid hydrolysis, partial acid hydrolysis, methylation and instrumental analysis. The results demonstrated that LCPA50-S1 is a heteropolysaccharide with a molecular weight of 1.58
KEYWORDS: Litchi chinensis, polysaccharide, structure characterization, immunomodulatory activity