BioScience Trends. 2015;9(3):205-212. (DOI: 10.5582/ddt.2015.01016)

Liposome encapsulated of temozolomide for the treatment of glioma tumor: preparation, characterization and evaluation.

Gao J, Wang Z, Liu H, Wang L, Huang G

Temozolomide plays a critical role in curing glioma at present. The purpose of this work was to develop a suitable drug delivery system which could prolong the half-life, improve the brain targeting, and reduce the systemic effect of the drug. Temozolomide-liposomes were formulated by the method of proliposomes. They were found to be relatively uniform in size of 156.70

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